Posts Tagged ‘egg collection’

Him: From 6 or 7, down to 5, down to 3… hope they continue to stick around…

March 13, 2013

We started another round of egg donation using the same donor as before. We had spoken with our doctor and she thought that it should be possible to use the same donor again even though we had only 9 eggs retrieved last time – but that they would modify the treatment to try and get better results.

So we managed to contact the donor (via the agency) and they were willing to try and help out again. So for the past couple of months the missus has been taking the nasal spray and tablets to get ready. Whilst I assume the donor has been doing likewise.

We had the 1st update on the progress last week, when they said they told us that the donor had 6-7 follicles and egg collection would take next week (which was yesterday morning).

This was bit of a shock for us, as we thought the results should have been better this time, but that was quite a low follicle count.

I went in to provide my main contribution to the process yesterday – the same day as the egg collection. I was shown to a different sperm collection room this time – it was a bit more basic, it didn’t have any a TV and DVD player… just some magazines in a drawer. And most of those were pretty tatty, with all the pages fallen apart. Still somehow, I managed to soldier on and provide my sample.

A bit later on, we got the call that my sample was OK and so they would use IVF rather than ICSI – also they had completed the egg collection and managed to retrieve 5 eggs.

Today we got the call that overnight 3 of the eggs had fertilised into embryos… so that’s the stage we’re at now. The next call should be in 2 days time, then we’ll find out how many made it that far, and if we’re going to attempt embryo transfer on that day.

Looking back at the last time, we had 4 embryos the day after egg collection, so we’re only 1 embryo down although we had 4 less eggs… still the numbers aren’t great, but I guess that there is still slim hope, for the moment.

Him: Produced my sample…

July 28, 2012

I woke up early today, earlier than I normally would on a weekend. I was due to go and produce my sperm sample which would later be combined with the donor’s eggs which were also due to be collected today.

We had some misapprehension, because just 4 days earlier, they had almost cancelled the treatment due to a “sub-optimal response” to the drug treatment, but apparently things had improved, although we didn’t have any details of to what level they had improved.

I went to the hospital and was greeted by a nurse, and then fairly quickly taken to the sperm collection room. She asked me to hang around afterwards in case there were any problems with the sample and then left me to it.

I took my time producing the sample (as I have done the previous few times), as I believe that a stronger orgasm produces a better quality sperm sample. I think I had read that theory on a website – after I went searching when my first ever sperm test had a bad result.

They had a couple of adult magazines, and some adult DVDs to help provide stimulation. One of the DVDs was a unlabelled computer writable computer DVD which had some internet porn burned onto it, as opposed to other fairly soft-porn commercial DVDs. I guess one of the other patients had brought it in and left it – it was a lot better than the other DVDs.

After I’d sent the sample of for processing, I waited for the results… and waited… and waited… for about 1.5 hours.

I had seen several couples come and go, and just as I was beginning to think that they had forgotten about me, the original nurse that I saw walked by and asked if anyone had spoken to me yet? (So perhaps they had forgotten about me?) I said no, and she said she’d get someone…

Shortly after, I found out that my sperm sample had been within normal parameters… concentration of 48 million per millilitre, and 64% motility – so after washing and preparation, about 31 million per millilitre. I was relieved, and I think that had also been the highest concentration sperm sample that I remember.

This meant that they would do IVF (i.e. allowing the sperm to mix with the eggs for fertilisation) rather ICSI (injecting the sperm into the eggs).

Also they mentioned that 9 eggs had been collected from the donor. I wasn’t expecting to find this out, so was relieved to hear that too. Perhaps this is why they took longer in getting back to me with the results – as they were waiting for that too?

I didn’t find out the quality of the eggs, as I forgot to ask about that – but in a way I’m happy not to know – ignorance is bliss, as they say.

Tomorrow we should get a call, letting us know how the egg fertilisation went, and when the likely embryo transfer will be… fingers crossed!

27 July 2012 – The night before

July 27, 2012

From chatting with the egg donation agency today, I decided that my husband should take a card and some flowers so our donor had them when she comes round after the egg collection tomorrow.

26 July 2012 – Mentally prepared for the worst

July 26, 2012

Good news from the hospital, our donor has been booked for her egg collection on Saturday. Frustratingly, when the hospital called, my mobile reception kept wavering while I was at work before cutting out completely. In the end, I suggested that they send me a text. My husband should go in at 9am on Saturday to produce his sample. I need to start my Cyclogest pessaries tomorrow (twice a day), continue with taking my Progynova tablets 3 times a day and stop taking my nasal spray.

Him: Payload delivered, good news so far…

June 30, 2010

I went this morning to give my sperm sample. I had abstained from any sexual activity for 2.5 days before, as was the roughly recommended amount. Shorter than this, and you might not have regenerated enough sperm. Longer than this and your sperm might be old and stale.

I missed their call back a couple of hours later, but after 10 minutes of panicking I managed to speak to them when they called again.

It was good news, they said that our share of the eggs was 7 eggs. Also it wouldn’t be necessary to do ICSI, due to the higher number of eggs and also my sperm quality was good. So they would go ahead with normal IVF.

We just have to keep our fingers crossed overnight now, and hope that they have good news for us tomorrow, to tell us whether the eggs have fertilised.

Him: My turn to do something!

June 28, 2010

The egg donor had their scan planned for last Friday, and we were told to expect a call on Friday afternoon. If she had progressed well enough, then they would do the egg collection the following Monday and I’d need to produce my sperm sample then.

In the end, she hadn’t progressed enough, and they scanned again today, and have called us to let us know that the egg collection will be on Wednesday. I’ll have to go in as well, and produce my sample – and the next day they will ring us back to let us know how many embryos (if any!) have fertilised.

After that, perhaps 2-5 days later, if all goes well, they’ll do the embryo transfer.

Luckily we haven’t had to wait too long since our initial IVF attempt. Although it has been ~9 months (?) since we put our names down on the egg sharing waiting list. Hopefully it will work out for us, based on the statistics the odds of the egg donor working should be much better than when we tried our own eggs. Only time will tell… fingers and toes crossed!

Her: 2 scans & quite a few blue pills later….

June 27, 2010

My first ultrasound scan confirmed that my ovaries had been inactivated and that my lining was thin. I was told to carry my Progynova (oestrogen) tablets with me in my handbag and expect a call a day later to confirm that I could start taking them.

A day later, the clinic called to tell me that the donor was ready to start her FSH injections. I was to take 1 Progynova tablet straight away, 1 before bed and then 3 a day (every 8 hours approx).

After 8 days of taking the Progynova, I went in for another scan to see how my lining was developing. I passed with flying colours – 11.5mm when the minimum needed is 7.5mm. Hopefully, this bodes well for a successful embryo transfer and implantation! I was to receive a telephone call a couple of days later to let me know whether the donor was ready for egg collection.

Given that the donor would be ready any day now, I went to pick up the rest of my prescription (Cyclogest and Gestone) from the hospital pharmacy. I thought it best to have the comfort that I had all the drugs I needed right away rather than risk ordering them from the supermarket pharmacy and not getting them in time. I only had a copy of my prescription as the original was with the supermarket pharmacy which had provided me with the drugs I have been taking so far. The pharmacy told me that by law, they can only provide me with the Cyclogest and Gestone from an original prescription so I had to go back upstairs to get another prescription prepared for me by the nurse.

We also had to settle our hospital bill in full (what a lot of money to dish out when there is a chance that we’d have nothing to show for it at the end of it all!) Success rates for treatment via egg donation at our clinic are currently 45-50% for a positive pregnancy test and 35-45% for a live birth.

I got a call on Friday to let me know that the donor wasn’t ready yet and will need to go in for another scan on Monday. In the meantime, I need to continue with my current drug regime.

It’s easier said then done, but while I wait for the next update from the clinic, I’m trying to stay positive, take it one step at a time and not look too far ahead.

Her: Heartbreak

February 20, 2010

Knowing that I couldn’t eat or drink anthing for 6 hours before my egg retrieval, I got up at 6am to sneak in some breakfast before I went back to bed again.

I had also been told to take a pain relief suppository (Voltarol) an hour before leaving home.

When we arrived at the hospital, we were shown to my Recovery room pretty much right away.  Well I say a room, but really it was an open plan cubicle surrounded by a curtain.   Inside, there was a gown, some foam slippers and a hair net for me to change into. 

A man in one of the cubicles directly opposite mine was telling one of the nurses that his partner was in agony – not really what I wanted to overhear shortly before my turn!  Another nurse was telling a lady that they were still counting her eggs.  As I waited with my husband, I felt both nervous and excited.  

We met with the doctor shortly before I was due to go into the egg collection room.  He put it simply to us – best case scenario was that we would get 3 eggs, worst case was 0 eggs.  What happens during egg collection is that a fine needle is used to empty the follicles in each ovary.  The fluid from each follicle is then examined under the microscope to check for any eggs.

Shortly before my husband was called to produce his semen sample, I followed the doctor blurrily into the egg collection room (as I couldn’t wear my contact lenses and I had to leave my glasses in the recovery room).  Inside, I met a number of other people involved in the procedure – a nurse, an anaesthetist and their assistant.

I was asked to confirm my name and date of birth before lying down.  Something that felt like a needle was inserted into a vein on the back of my right hand.  The anaesthetist explained the medication that would be given to me – a painkiller, sedative and anti-sickness medication.  At the same time, an oxygen mask was put over my mouth and I was attached to the equipment that would monitor my heart rate and blood pressure.  Everything seemed to happen so quickly and efficiently.

I remember chatting to the anaesthetist about where I lived and him telling me that he used to live near there.  The doctor was asking about whether something was ready.  Then the sedative must have taken efect as I was overcome by the weirdest light-headed feeling, the ceiling panels I was staring up at started to move like a conveyor belt.

When I opened my eyes again, I was back in the recovery room with the nurse who had greeted us when we first arrived.   My husband hadn’t returned yet and I asked what time it was – it was about 20/25 minutes after I had entered the egg collection room.  He soon arrived though and asked me how I was feeling.  I actually felt fine – like I had been woken up abruptly from a dream and was relieved and surprised that I felt no pain other than from the catheter that was still attached to my right hand.  I only realised later when I got up to get changed that I had bled slightly from the procedure.  This had come from the site where the needle had passed through the vaginal wall during egg collection.

I was attached to a machine which continued to monitor my heart rate and blood pressure while I rested for a hour or so. 

We had just finished some tea and biscuits when the doctor came in to explain that the procedure had been straight forward to perform.  However, when it came to it, I only had one follicle and when this was checked out, there was no egg to be found.  Needless to day, this was an outcome far worse than I had anticipated.  I knew 0 eggs was a possibility, but it never occurred to me that I would lose 2 follicles!

The doctor put it down to the fact that the other 2 follicles had probably run out of steam.  Fair enough as on average,  egg collection happens after 13-15 days of stimulation.  I had been doing maximum dose Gonal-F injections for over a week longer.  Although the cycle failed, I have no regrets that we continued for as long as we did as this was the only way that we would know for sure that we had tried our very best. 

It will take a bit of time for us to recover from such a massive disappointment.  Since leaving the hospital, I have been  overcome by feelings of sadness that hit me out of the blue.  At first, even my husband’s hugs which are always a reliable source of comfort were not enough to pull me out of these moments of deep melancholy.  Instead, they served to remind me of our disappointing experience.  It was my husband’s birthday a couple of days ago and I am so sorry that I wasn’t able to make his birthday wish come true.  If nothing else, this process has brought us closer.  He made time to accompany me at every one of my 7 scans.  I have never been more grateful for his love and support.

So here ends our first and maybe our only IVF cycle.  We have a follow up appointment with the consultant gynaecologist on the 10 March to assess our treatment.  It will do me good to return to a bit of normality for a month or two (Yay, no more injections or scans!)  Some kind of holiday would also be good.

I am doubtful that it would be worthwhile having another go at IVF but let’s see what the consultant says.  I would like to understand better why our cycle failed and whether there are any other options available to us before embarking on the egg donation route. 

I need reassurance that my body is able to produce eggs.  If it is, this cycle hasn’t given us any information on what the the quality of my eggs is like.  Also, say they were able to collect an egg or two, would my husband’s sperm have fertilised them to produce an embryo?

Her: Lucky Scan 7

February 17, 2010

Wow!  7 scans and 23 Gonal-F injections later, we finally have the go-ahead for egg collection.

Today, we bumped into the consultant gynaecologist who did our initial consultation last May while we were in the waiting room.  She stopped to ask us how things were going (slowly but surely) and wished us luck.  That was nice.

Before we left the clinic today, we were told that there would be a meeting this afternoon to agree what I need to do next to prepare for egg collection.  The nurse called at 5.15pm which was late enough to make me think that she had forgotten about me.

I took my last dose of the Nafarelin nasal spray earlier this evening and will relace my usual Gonal-F injection with the hCG (Ovitrelle) injection at 11pm tonight (38 hours before my planned egg collection).  This final injection causes the final stages of egg ripening to take place.

Up to today, I really thought we would end up being the one in ten statistic that they quote in the brochure for having our cycle cancelled.  I have approached this whole process as a series of hurdles to negotiate – what a high one the first one has been but we’ve made it!  The nurse today made a comment about how we now stand as good a chance as any other couple of a successful IVF cycle.  I, on the other hand am still erring on the side of caution.  We only have 3 follicles to play with and we don’t yet know whether they will all contain eggs or what the quality of my eggs are like.

Her: It ain’t over yet!

February 12, 2010

I can’t believe that they have asked me to come in for another scan on 15 Feb (that will be the sixth one)!

Despite having so many scans, I still have no idea what follicles are meant to look like on the monitor.   I feel silly having to admit that I’m losing track of how many follicles are in which ovary (it’s not like I have so many to keep track of!)  Apparently, the scan today showed 2 follicles in my right ovary which had grown 2mm since last time, one in my left ovary seems to have peaked at a size that is too small.  If the two “good” follicles grow by the same amount between now and Monday, that will take them close enough to the threshold size required for egg collection.

Even after hearing that my follicles were continuing to grow, I thought surely it’s too little too late given that it is now Day 24 of my cycle.  I was told that although it was unusual for my ovaries to take so long to respond to stimulation, this should not impact the success rate of the IVF process. 

When we left the ultrasound scan room, I really was expecting the worst but part of me was also relieved that I would no longer have to worry about having to explain why I had to keep going into work late.

We could have so easily conceded to cancelling the cycle on Wednesday given the doctors advice but against the odds, egg collection appears to still be a possibility.